Against 422 other 4-cyl cars rated 2023–2025, the QX50 sits right on their 26.5 mpg average. Averaged over the years each was sold, the most economical engine since 2014, the 2L 4-cyl (2019–2025), does 26.1 mpg and the thirstiest, the 3.7L 6-cyl (2014–2017), 20: $449 a year apart.
Every Infiniti QX50 engine, compared
Yearly cost assumes 12,000 miles at $3.20 a gallon.
| Engine | Combined | City / Highway | Years | Fuel per year |
|---|---|---|---|---|
| 2L 4-cyl | 23.1 / 29.3 | 2019–2025 | $1,471 | |
| 3.7L 6-cyl | 17.3 / 24.5 | 2014–2017 | $1,920 |
What that actually costs
Against its rivals in the same model years, the Honda HR-V gets 28 mpg, next to 26 mpg for the 2025 QX50. The QX50 costs the most of them to run: $106 a year more than the Honda HR-V.
| Measure | Value |
|---|---|
| Cost per mile (2025) | $0.123 |
| Fuel per year | $1,477 |
| Fuel over five years | $7,385 |
| Against other 4-cyl cars, 2023–2025 | +$28 a year |
| EPA's own estimate | $3,268 a year |
City or highway — who is this car for
The 2025 Infiniti QX50 gives up 6 mpg in town: 29 on the highway against 23 in the city, $346 a year if every mile were city driving.
| Measure | Value | Reading |
|---|---|---|
| City (2025) | 23 mpg | $1,670 a year if you only drive in town |
| Highway | 29 mpg | $1,324 a year if you mostly commute |
| Gap | +6 mpg (26%) | Typical for its type |
How the QX50 changed over the years
The QX50 peaked in 2019 at 27 mpg (24 city, 31 highway) and was at its thirstiest in 2017 at 20 — 7 mpg apart, or $498 a year in fuel between buying one year and the other. The 2025 car does 26.
| Model year | Combined | City / Highway | Engines offered | Fuel per year |
|---|---|---|---|---|
| 2025 | 23 / 29 | 1 | $1,477 | |
| 2024 | 23 / 29 | 1 | $1,477 | |
| 2023 | 23 / 29 | 1 | $1,477 | |
| 2022 | 23 / 29 | 1 | $1,477 | |
| 2021 | 23 / 29 | 1 | $1,477 | |
| 2020 | 23 / 29 | 1 | $1,477 | |
| 2019 | 24 / 31 | 1 | $1,422 | |
| 2017 | 17 / 24 | 1 | $1,920 | |
| 2016 | 17 / 24 | 1 | $1,920 | |
| 2015 | 17 / 25 | 1 | $1,920 | |
| 2014 | 18 / 25 | 1 | $1,920 |
MPG is a number. Dollars per year is the answer.
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How we count
This page rests on 11 EPA ratings of the Infiniti QX50 — 2 engines across 2014–2025. The mileage is EPA's laboratory figure, unchanged; the yearly bill is ours, at 12,000 miles and $3.20 a gallon, against EPA's own estimate of $3,268. Full method.
Frequently asked questions
What mpg does the 2025 Infiniti QX50 get?
26 mpg combined, 23 city and 29 highway, per EPA. Across every year since 2014 the QX50 has averaged 23.9 mpg.
Is the 2025 QX50 more efficient than the 2024?
About the same: 26 against 26 mpg combined.
Which QX50 year has the best gas mileage?
The 2019, at 27 mpg combined (24 city, 31 highway).
Does the QX50 get better gas mileage than the Honda HR-V?
No: 26 mpg for the 2025 QX50 against 28 for the 2026 Honda HR-V, about $106 a year more to run.
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