I-280

Isuzu i-280 MPG

Isuzu i-280 gas mileage averages 21 mpg combined — about $1,829 a year in fuel at today's prices, or $9,145 over five years. Below: every engine compared, because the gap between versions is usually wider than the gap between models.

EPA fueleconomy.gov · 1 engines · 2006–2006 · Updated Sep 19, 2026
Quick answer

The Isuzu i-280 does 21 mpg combined (18 city, 25 highway), which works out to about $1,829 a year in fuel at $3.20 a gallon and 12,000 miles. Against other 4-cyl cars it sits below the average of 25.7 mpg.

Every Isuzu i-280 engine, compared

The Isuzu i-280 was rated in a single specification, so its gas mileage does not vary by version — only by model year. Yearly cost assumes 12,000 miles at $3.20 a gallon.

FIG.01·Isuzu i-280 gas mileage by engine
EngineCombinedCity / HighwayYearsFuel per year
2.8L 4-cyl2118 / 252006–2006$1,829
ROWS 1·SOURCE EPA fueleconomy.gov + ForCar

What that actually costs

The Isuzu i-280 burns a gallon every 21 miles, so 12,000 miles takes about 571 gallons a year. At $3.20 that is what the table below adds up to.

FIG.02·Isuzu i-280 fuel cost
MeasureValue
Cost per mile$0.152
Fuel per year$1,829
Fuel over five years$9,145
Against other 4-cyl cars+$335 a year
EPA's own estimate$2,950 a year
ROWS 5·SOURCE ForCar, computed from EPA ratings

City or highway — who is this car for

The Isuzu i-280 gives up 7 mpg the moment you leave the motorway — 25 out there against 18 in town, a 39% drop worth $597 a year. A wide gap punishes stop-and-start traffic; a narrow one means the car doesn't care where you drive it.

FIG.03·Isuzu i-280 city versus highway
MeasureValueReading
City18 mpg$2,133 a year if you only drive in town
Highway25 mpg$1,536 a year if you mostly commute
Gap+7 mpg (39%)Wide — this car dislikes traffic
ROWS 3·SOURCE EPA fueleconomy.gov + ForCar

How the i-280 changed over the years

Combined figure across the 1 model year the i-280 was rated in, all of them at 21 mpg.

FIG.04·Isuzu i-280 gas mileage by model year
Model yearCombinedCity / HighwayEngines offeredFuel per year
20062118 / 251$1,829
ROWS 1·SOURCE EPA fueleconomy.gov + ForCar
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How we count

This page rests on 1 EPA ratings of the Isuzu i-280 — 1 engine across 2006–2006. The mileage is EPA's laboratory figure, unchanged; the yearly bill is ours, at 12,000 miles and $3.20 a gallon, against EPA's own estimate of $2,950. Full method.

Frequently asked questions

What mpg does the Isuzu i-280 get?

21 mpg combined on average — 18 in the city and 25 on the highway, per EPA ratings across 2006–2006.

How much does a Isuzu i-280 cost in fuel per year?

About $1,829 at 12,000 miles and $3.20 a gallon — roughly $9,145 over five years, or 0.152 dollars a mile.

Which i-280 engine is the most economical?

The 2.8L 4-cyl at 21 mpg.

Is the i-280 good on fuel compared with similar cars?

Against other 4-cyl cars it sits below the average of 25.7 mpg, computed across 4765 ratings.

Are these real-world i-280 figures?

No — they are EPA laboratory ratings, the same ones printed on the window sticker, and EPA's own annual fuel estimate for the Isuzu i-280 is $2,950 against the $1,829 we compute at 12,000 miles. Expect a little worse in practice: the spread between the city and highway figures is smaller than the spread between two drivers of the same one.

Gas mileage ratings from EPA fueleconomy.gov, unadjusted. Running cost computed by ForCar at 12,000 miles a year and $3.20 a gallon. Last updated Sep 2026. — ForCar Reviewed by , founder of ForCar.
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