I-280

Isuzu i-280 MPG

The Isuzu i-280 averages 21.0 mpg combined — about $1,829 a year in fuel at today's prices, or $9,145 over five years. Below: every engine compared, because the gap between versions is usually wider than the gap between models.

EPA fueleconomy.gov · 1 engines · 2006–2006 · Updated Aug 5, 2026
Quick answer

The Isuzu i-280 does 21.0 mpg combined (18.0 city, 25.0 highway), which works out to about $1,829 a year in fuel at $3.20 a gallon and 12,000 miles. Against other 4-cyl cars it sits below the average of 25.4 mpg.

Every Isuzu i-280 engine, compared

Picking the right version of the same car often saves more fuel than picking a different car altogether. Yearly cost assumes 12,000 miles at $3.20 a gallon.

FIG.01·Isuzu i-280 fuel economy by engine
EngineCombinedCity / HighwayYearsFuel per year
2.8L 4-cyl2118 / 252006–2006$1,829
ROWS 1·SOURCE EPA fueleconomy.gov + ForCar

What that actually costs

Miles per gallon is an abstraction; the fuel bill is not. Here it is in money, at 12,000 miles a year and $3.20 a gallon.

FIG.02·Isuzu i-280 fuel cost
MeasureValue
Cost per mile$0.152
Fuel per year$1,829
Fuel over five years$9,145
Against other 4-cyl cars+$317 a year
EPA's own estimate$2,950 a year
ROWS 5·SOURCE ForCar, computed from EPA ratings

City or highway — who is this car for

The gap between city and highway figures tells you whom the car suits. A wide gap punishes stop-and-start traffic; a narrow one means the car doesn't care where you drive it.

FIG.03·Isuzu i-280 city versus highway
MeasureValueReading
City18.0 mpg$2,133 a year if you only drive in town
Highway25.0 mpg$1,536 a year if you mostly commute
Gap+7 mpg (39%)Wide — this car dislikes traffic
ROWS 3·SOURCE EPA fueleconomy.gov + ForCar

How the i-280 changed over the years

Combined figure by model year. Jumps usually mark a new generation or a new engine; dips often mean a heavier body or added all-wheel drive.

FIG.04·Isuzu i-280 fuel economy by model year
Model yearCombinedCity / HighwayEngines offeredFuel per year
20062118 / 251$1,829
ROWS 1·SOURCE EPA fueleconomy.gov + ForCar
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How we count

Fuel-economy figures come from EPA fueleconomy.gov — the same laboratory numbers printed on the window sticker. We don't adjust them; real-world consumption depends on how and where you drive.

What we add is money. Yearly cost assumes 12,000 miles at $3.20 a gallon — change either and the ranking stays, only the size of the bill moves. Cost per mile is the same figure divided out, useful when comparing a commute against a weekend car.

Frequently asked questions

What mpg does the Isuzu i-280 get?

21.0 mpg combined on average — 18.0 in the city and 25.0 on the highway, per EPA ratings across 2006–2006.

How much does a Isuzu i-280 cost in fuel per year?

About $1,829 at 12,000 miles and $3.20 a gallon — roughly $9,145 over five years, or 0.152 dollars a mile.

Which i-280 engine is the most economical?

The 2.8L 4-cyl at 21 mpg.

Is the i-280 good on fuel compared with similar cars?

Against other 4-cyl cars it sits below the average of 25.4 mpg, computed across 6877 ratings.

Are these real-world figures?

No — they are EPA laboratory ratings, the same ones on the window sticker. Real consumption depends on driving style, terrain, load and weather, and is typically a little worse.

Fuel-economy ratings from EPA fueleconomy.gov, unadjusted. Fuel cost computed by ForCar at 12,000 miles a year and $3.20 a gallon. Last updated Aug 2026. — ForCar Reviewed by , founder of ForCar.