Infiniti M45 MPG

The 2010 Infiniti M45 gets 18 mpg combined (16 city, 21 highway): about $2,133 a year in fuel at $3.20 a gallon and 12,000 miles.

EPA fueleconomy.gov · 1 engines · 2003–2010 · Updated Nov 3, 2026
Quick answer

Against 362 other V8 cars rated 2008–2010, the M45 beats their 15.9 mpg average by 2.1 mpg, about $282 a year.

Every Infiniti M45 engine, compared

The Infiniti M45 was rated in a single specification, so its gas mileage does not vary by version — only by model year. Yearly cost assumes 12,000 miles at $3.20 a gallon.

FIG.01·Infiniti M45 gas mileage by engine
EngineCombinedCity / HighwayYearsFuel per year
4.5L 8-cyl1816 / 21.32003–2010$2,133
ROWS 1·SOURCE EPA fueleconomy.gov + ForCar

What that actually costs

Against its rivals in the same model years, the Chrysler 300 gets 20 mpg, the Hyundai Sonata 26.2 mpg and the Chevrolet Impala 21.8 mpg, next to 18 mpg for the 2010 M45. The M45 costs the most of them to run: $667 a year more than the Hyundai Sonata.

FIG.02·Infiniti M45 fuel cost
MeasureValue
Cost per mile (2010)$0.178
Fuel per year$2,133
Fuel over five years$10,665
Against other V8 cars, 2008–2010−$282 a year
EPA's own estimate$4,300 a year
ROWS 5·SOURCE ForCar, computed from EPA ratings

City or highway — who is this car for

The 2010 Infiniti M45 gives up 5 mpg in town: 21 on the highway against 16 in the city, $571 a year if every mile were city driving.

FIG.03·Infiniti M45 city versus highway
MeasureValueReading
City (2010)16 mpg$2,400 a year if you only drive in town
Highway21 mpg$1,829 a year if you mostly commute
Gap+5 mpg (31%)Wide — this car dislikes traffic
ROWS 3·SOURCE EPA fueleconomy.gov + ForCar

How the M45 changed over the years

Combined figure across the 7 model years the M45 was rated in, all of them at 18 mpg.

FIG.04·Infiniti M45 gas mileage by model year
Model yearCombinedCity / HighwayEngines offeredFuel per year
20101816 / 211$2,133
20091816 / 211$2,133
20081816 / 211$2,133
20071816 / 211$2,133
20061816 / 211$2,133
20041816 / 221$2,133
20031816 / 221$2,133
ROWS 7·SOURCE EPA fueleconomy.gov + ForCar
Upgrade to Pro

MPG is a number. Dollars per year is the answer.

  • Fuel profile built from your actual mileage and local prices
  • Fuel tracker: what you really spend, month by month
  • Insurance and fuel folded into 5-year cost to own
  • Compare any two cars on total cost, not sticker price
  • No ads, no tracking — and much more
Free plan available — no credit card needed

How we count

This page rests on 7 EPA ratings of the Infiniti M45 — 1 engine across 2003–2010. The mileage is EPA's laboratory figure, unchanged; the yearly bill is ours, at 12,000 miles and $3.20 a gallon, against EPA's own estimate of $4,300. Full method.

Frequently asked questions

What mpg does the 2010 Infiniti M45 get?

18 mpg combined, 16 city and 21 highway, per EPA. Across every year since 2003 the M45 has averaged 18 mpg.

Is the 2010 M45 more efficient than the 2009?

About the same: 18 against 18 mpg combined.

Does the M45 get better gas mileage than the Chrysler 300?

No: 18 mpg for the 2010 M45 against 20 for the 2011 Chrysler 300, about $213 a year more to run.

Gas mileage ratings from EPA fueleconomy.gov, unadjusted. Running cost computed by ForCar at 12,000 miles a year and $3.20 a gallon. Last updated Nov 2026. — ForCar Reviewed by , founder of ForCar.
Found this useful?

Mark ForCar as a preferred source and our data shows up first in your Google results. One click, no account.

Prefer ForCar →