CLS-CLASS

Mercedes-Benz CLS-Class MPG

Mercedes-Benz CLS-Class gas mileage averages 20.7 mpg combined — about $1,855 a year in fuel at today's prices, or $9,275 over five years. Below: every engine compared, because the gap between versions is usually wider than the gap between models.

EPA fueleconomy.gov · 5 engines · 2006–2023 · Updated Sep 19, 2026
Quick answer

The Mercedes-Benz CLS-Class does 20.7 mpg combined (18.1 city, 25.7 highway), which works out to about $1,855 a year in fuel at $3.20 a gallon and 12,000 miles. Engine choice matters more than you'd think: 3L 6-cyl Hybrid does 25.6 mpg while 5.5L 8-cyl does 16 — a difference of $900 a year. Against other V8 cars it sits above the average of 16.1 mpg.

Every Mercedes-Benz CLS-Class engine, compared

Gas mileage on the Mercedes-Benz CLS-Class ranges from 25.6 down to 16 depending on which engine sits under the bonnet — a spread of $900 a year across 5 versions of the same car. Picking the right one often saves more fuel than picking a different car altogether. Yearly cost assumes 12,000 miles at $3.20 a gallon.

FIG.01·Mercedes-Benz CLS-Class gas mileage by engine
EngineCombinedCity / HighwayYearsFuel per year
3L 6-cyl Hybrid25.623 / 30.42019–2023$1,500
3L 6-cyl2420 / 292015–2016$1,600
4.7L 8-cyl20.317.6 / 25.62012–2018$1,892
5L 8-cyl1614 / 202006–2006$2,400
5.5L 8-cyl1614 / 20.82007–2011$2,400
ROWS 5·SOURCE EPA fueleconomy.gov + ForCar

What that actually costs

The Mercedes-Benz CLS-Class burns a gallon every 20.7 miles, so 12,000 miles takes about 580 gallons a year. At $3.20 that is what the table below adds up to.

FIG.02·Mercedes-Benz CLS-Class fuel cost
MeasureValue
Cost per mile$0.155
Fuel per year$1,855
Fuel over five years$9,275
Against other V8 cars−$530 a year
EPA's own estimate$3,840 a year
ROWS 5·SOURCE ForCar, computed from EPA ratings

City or highway — who is this car for

The Mercedes-Benz CLS-Class gives up 7.6 mpg the moment you leave the motorway — 25.7 out there against 18.1 in town, a 42% drop worth $628 a year. A wide gap punishes stop-and-start traffic; a narrow one means the car doesn't care where you drive it.

FIG.03·Mercedes-Benz CLS-Class city versus highway
MeasureValueReading
City18.1 mpg$2,122 a year if you only drive in town
Highway25.7 mpg$1,494 a year if you mostly commute
Gap+7.6 mpg (42%)Wide — this car dislikes traffic
ROWS 3·SOURCE EPA fueleconomy.gov + ForCar

How the CLS-Class changed over the years

The CLS-Class peaked in 2021 at 26 mpg (23 city, 30 highway) and was at its thirstiest in 2011 at 16 — 10 mpg apart, or $923 a year in fuel between buying one year and the other. The 2023 car does 25. Jumps usually mark a new generation or a new engine; dips often mean a heavier body or added all-wheel drive.

FIG.04·Mercedes-Benz CLS-Class gas mileage by model year
Model yearCombinedCity / HighwayEngines offeredFuel per year
20232522 / 301$1,536
20222522 / 301$1,536
20212623 / 301$1,477
20202624 / 311$1,477
20192624 / 311$1,477
20182118 / 261$1,829
20172118 / 261$1,829
20162219 / 27.52$1,745
20152219 / 27.52$1,745
20142017 / 251$1,920
20132017 / 251$1,920
20122017 / 251$1,920
20111614 / 211$2,400
20101614 / 211$2,400
20091614 / 211$2,400
20081614 / 211$2,400
20071614 / 201$2,400
20061614 / 201$2,400
ROWS 18·SOURCE EPA fueleconomy.gov + ForCar
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How we count

This page rests on 20 EPA ratings of the Mercedes-Benz CLS-Class — 5 engines across 2006–2023. The mileage is EPA's laboratory figure, unchanged; the yearly bill is ours, at 12,000 miles and $3.20 a gallon, against EPA's own estimate of $3,840. Full method.

Frequently asked questions

What mpg does the Mercedes-Benz CLS-Class get?

20.7 mpg combined on average — 18.1 in the city and 25.7 on the highway, per EPA ratings across 2006–2023.

How much does a Mercedes-Benz CLS-Class cost in fuel per year?

About $1,855 at 12,000 miles and $3.20 a gallon — roughly $9,275 over five years, or 0.155 dollars a mile.

Which CLS-Class engine is the most economical?

The 3L 6-cyl Hybrid at 25.6 mpg, against 16 for the 5.5L 8-cyl — a difference of about $900 a year.

Is the CLS-Class good on fuel compared with similar cars?

Against other V8 cars it sits above the average of 16.1 mpg, computed across 3323 ratings.

Are these real-world CLS-Class figures?

No — they are EPA laboratory ratings, the same ones printed on the window sticker, and EPA's own annual fuel estimate for the Mercedes-Benz CLS-Class is $3,840 against the $1,855 we compute at 12,000 miles. Expect a little worse in practice: the spread between the 26 and 16 mpg versions of this car is smaller than the spread between two drivers of the same one.

Gas mileage ratings from EPA fueleconomy.gov, unadjusted. Running cost computed by ForCar at 12,000 miles a year and $3.20 a gallon. Last updated Sep 2026. — ForCar Reviewed by , founder of ForCar.
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